Figure 3. Common and species-specific mechanisms of immunomodulation by human herpesvirus 6A and human herpesvirus 6B.

Although the two viruses exert common effects on the immune system (Venn diagram intersection), they also exhibit specific activities (left and right panels for HHV-6A and -6B, respectively).

^†It has to be emphasized that these mechanisms, listed under species-specific activities, were tested exclusively on a single viral species and therefore cannot be definitively considered specific.

DC: Dendritic cell; HHV: Human herpesvirus.