Table 1.
Clinical characteristics and imaging findings based on the presence and location of the SVS
| Variables | M1 proximal SVS | M1 distal SVS | MCA distal SVS | No SVS | p |
|---|---|---|---|---|---|
| (n = 25) | (n = 22) | (n = 44) | (n = 67) | ||
| Median age, years | 79 (73 – 83) | 76 (66 – 86) | 79 (74 – 84) | 77 (70 – 85) | 0.960 |
| Male sex, n | 14 (56) | 15 (68) | 21 (48) | 34 (51) | 0.431 |
| Median NIHSS score on admission | 20 (15 – 23) | 17 (12 – 22) | 13 (7 – 19) | 16 (10 – 20) | 0.001 |
| Premorbid mRS score 0 – 1, n | 20 (75) | 18 (82) | 32 (73) | 49 (73) | 0.771 |
| Interval from onset to thrombolysis, min | 153 (131 – 167) | 146 (120 – 167) | 145 (120 – 175) | 143 (115 – 172) | 0.894 |
| Intra-arterial intervention, n | 4 (16) | 4 (18) | 5 (11) | 10 (15) | 0.887 |
| Vascular risk factor, n | |||||
| Hypertension | 11 (44) | 14 (64) | 34 (77) | 47 (70) | 0.037 |
| Diabetes mellitus | 3 (12) | 3 (14) | 8 (18) | 18 (27) | 0.310 |
| Hyperlipidemia | 3 (12) | 6 (27) | 9 (21) | 15 (22) | 0.608 |
| Atrial fibrillation | 18 (72) | 14 (64) | 25 (57) | 35 (52) | 0.356 |
| Past medication, n | |||||
| Antiplatelet therapy | 7 (28) | 6 (27) | 8 (18) | 19 (28) | 0.648 |
| Anticoagulation therapy | 4 (16) | 2 (9) | 5 (11) | 5 (8) | 0.666 |
| Median systolic blood pressure, mm Hg | 152 (145 – 168) | 156 (138 – 167) | 147 (131 – 164) | 156 (139 – 170) | 0.334 |
| Median diastolic blood pressure, mm Hg | 82 (68 – 95) | 81 (70 – 98) | 81 (70 – 91) | 84 (70 – 92) | 0.860 |
| Stroke etiology, n | |||||
| Large-artery atherosclerosis | 4 (16) | 3 (14) | 2 (5) | 7 (10) | 0.430 |
| Cardioembolism | 18 (72) | 14 (64) | 28 (64) | 38 (57) | 0.587 |
| Other or undetermined | 3 (12) | 5 (23) | 14 (32) | 22 (33) | 0.205 |
| Portion of occlusion, n | |||||
| ICA | 18 (72) | 3 (14) | 4 (9) | 18 (27) | <0.001 |
| M1 | 7 (28) | 19 (86) | 17 (39) | 26 (39) | <0.001 |
| M2 | 0 (0) | 0 (0) | 23 (52) | 23 (34) | <0.001 |
| DWI findings | |||||
| Median ASPECTS | 7 (3 – 9) | 7 (5 – 9) | 8 (6 – 10) | 8 (6 – 10) | 0.095 |
| Median initial ischemic volume, ml | 12.3 (4.0 – 56.3) | 13.2 (2.1 – 42.2) | 4.1 (1.0 – 21.5) | 7.1 (1.6 – 35.8) | 0.091 |
| Early recanalization | |||||
| No | 24 (96) | 16 (73) | 25 (57) | 36 (54) | <0.001 |
| Partial | 1 (4) | 5 (23) | 12 (27) | 19 (28) | 0.088 |
| Complete | 0 (0) | 1 (4) | 7 (16) | 12 (18) | 0.071 |
| Clinical outcome at 3 months | |||||
| mRS score 0 – 1, n | 0/16 (0) | 5/14 (36) | 12/25 (48) | 13/40 (33) | 0.014 |
Figures in parentheses are percentages or interquartile ranges. M1 indicates the horizontal portion of the MCA, M2 the sylvian portion of the MCA. ASPECTS = Alberta Stroke Program Early Computed Tomography Score.