Table 1. MMR repair activity during S and G2/M stages of the cell cycle.

		Mutation rate (fold increase)*
Relevant genotype	Strain RDKY	Thr +	Lys +	CanR
msh3 Δ	7672	5.1 [3.4-6.4] × 10−8 (1)	7.8 [6.0-11.3] × 10−8 (1)	8.0 [6.2-16.8] × 10−8 (1)
msh3Δ msh6Δ	7674	5.5 [3.6-8.6] × 10−6 (108)	3.3 [2.2-4.6] × 10−5 (423)	2.4 [1.6-3.8] × 10−6 (30)
G2/M-MSH6 msh3 Δ	7676	4.3 [3.3-5.5] × 10−6 (84)	2.9 [1.7-4.7] × 10−5 (372)	2.9 [2.1-4.3] × 10−6 (36)
S-MSH6 msh3 Δ	7678	6.9 [4.8-8.9] × 10−7 (13)	2.6 [1.8-4.0] × 10−6 (33)	4.1 [3.1-5.1] × 10−7 (5)
G2/M-degmut-MSH6 msh3 Δ	7680	2.5 [1.1-3.1] × 10−7 (5)	3.9 [1.5-5.0] × 10−7 (5)	2.1 [1.6-3.4] × 10−7 (3)
msh3Δ lys2-10ALATE	7681	4.8 [2.3-5.9] × 10−8 (1)	1.1 [0.6-2.5] × 10−7 (1)	9.7 [5.2-12.5] × 10−8 (1)
msh3Δ msh6Δ lys2-10ALATE	7688	4.8 [2.5-10.8] × 10−6 (93)	7.3 [2.1-11.1] × 10−5 (932)	2.1 [1.0-2.8] × 10−6 (26)
G2/M-MSH6 msh3Δ lys2-10ALATE	7682	3.4 [2.5-4.2] × 10−6 (68)	8.8 [5.3-17.9] × 10−7 (11)	1.8 [1.0-2.4] × 10−6 (22)
S-MSH6 msh3Δ lys2-10ALATE	7684	8.1 [5.6-10] × 10−7 (16)	1.2 [0.8-1.8] × 10−5 (155)	3.2 [1.9-4.4] × 10−7 (4)

^*Median rates of hom3-10 (Thr⁺) and lys2-10A (Lys⁺) reversion and inactivation of CAN1 (Can^R) with 95% C.I. in square brackets and fold increase relative to the msh3Δ strain in parentheses.