Table 3. MMR suppression of duplication mediated GCRs during S- and G2/M.
Relevant genotype |
Strain RDKY |
GCR rate* (fold increase) |
---|---|---|
wild-type | 6678 | 4.13 [3.1-6.6] × 10−8 (1) |
msh6 Δ | 6714 | 2.18 [1.6-2.7] × 10−7 (5.3) |
G2/M-MSH6 | 7685 | 4.00 [2.8-7.4] × 10−8 (1.0) |
S-MSH6 | 7686 | 9.11 [5.7-16.4] × 10−8 (2.2) |
Rate of 5FOAR CanR progeny. The number in parentheses represents the fold increase relative to the wild-type GCR rate.