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Immunization with ovalbumin (OVA) and human α1-anti-trypsin (hA1AT) resulted in generally higher level IgM and IgG titers measured by ELISA, more antigen specific IgM and IgG producing B cells determined by ELISPOT, and larger spleen in Tg rabbits as compared to their wt controls (* P<0.05; ** P<0.01).
