Table 2. Effect of P1736 on Liver safety parameters in db/db mice.

Treatment	Liver Weight (gm)	Plasma ALT (U/L)	Plasma AST (U/L)
Vehicle	1.8 + 0.10	91.2 + 12.7	100.6 + 8.8
P1736 (150mg/kg)	2.1+ 0.10	99.0 + 8.5	84.6 + 2.6
Metformin (150mg/kg)	2.1 + 0.08	75.3 + 6.4	101.7 + 8.4