Figure 3. Diagnostic potential of deregulated circulating miRNAs for benign and malignant breast tumors (cohort B).
In ROC curve analysis individual circulating miRNAs were found to have discriminatory accuracy of 0.59–0.75. A panel of seven circulating miRNAs (miR-127-3p, miR-148b, miR-376a, miR-376c, miR-409-3p, miR-652 and miR-801) discriminated between healthy women and those with benign and malignant breast tumors with an AUC of 0.81 and the discriminatory power was superior in younger women (AUC = 0.86).
