Figure 8. Generation of asymmetric (85/15) blood streams at micro-scale stenosis to investigate role of the upper blood stream as a function of (hematocrit) on platelet aggregation.

Platelet aggegation response was found to be a function of the hematocrit in the upper layer. The hematocrit in the upper stream of 85% ( ) was modified from 0% (buffer solution) to 45%. The bottom stream of 15% ( ) was infused with whole blood with the platelet inhibitors of aggregation (Amplification loop blocked ALB). The platelet aggregation response is effectively modulated by the upper layer and its concentration of red cells.