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. 2013 Oct 23;8(10):e76684. doi: 10.1371/journal.pone.0076684

Figure 4. Steroid-mediated action of Fsh on the steady-state level of mRNA transcripts measured by qPCR.

Figure 4

slc26a4, vt1, mmp19 and wisp1 and inha genes segregate in Cluster 1. The inhba gene belongs to Cluster 4. Three additional transcripts (fshr, lhcgr and igfbp6) previously demonstrated as up-regulated by gonadotropins are found to behave like genes in Cluster 1. Note that Fsh regulations of inha, wisp1 and igfbp6 are only partially lost in the presence of Tri. Bars represent mean ± SD of 5 to 6 replicates. Expression data were normalized to the reference gene rps15. Different letters indicate that treatments are significantly different as determined by non-parametric Mann & Whitney test.