Table 1. Summary of DSD improvements of all four methods in 2-fold cross validation (mean and standard deviation in percentage) for the PPI network of S. cerevisiae.

	MIPS 1		MIPS 2		MIPS 3
	Accuracy	F1 score	Accuracy	F1 score	Accuracy	F1
Majority Vote (MV)	50.0±0.5	41.6±0.2	40.7±0.5	30.7±0.4	38.4±0.4	29.5±0.4
MV with DSD	63.7±0.4	47.2±0.2	49.3±0.5	35.6±0.2	43.8±0.4	32.3±0.3
MV (weighted DSD)	63.2±0.5	48.1±0.3	50.6±0.4	36.6±0.2	45.3±0.3	33.6±0.2
Neighborhood (NH)	43.3±0.3	34.5±0.2	32.4±0.6	26.1±0.3	31.3±0.5	24.8±0.3
NH with DSD	51.5±0.4	40.6±0.3	34.8±0.5	27.7±0.2	32.6±0.6	25.1±0.3
Multi-cut	55.2±0.4	42.1±0.2	42.0±0.6	28.1±0.2	36.6±0.4	24.8±0.3
Multi-cut with DSD	58.3±0.3	42.2±0.2	44.6±0.4	29.6±0.1	38.2±0.3	25.3±0.2
Functional Flow (FF)	50.5±0.6	37.0±0.3	32.1±0.4	22.6±0.3	25.4±0.6	18.3±0.3
FF with DSD	54.0±0.4	40.8±0.2	38.3±0.3	27.1±0.3	31.5±0.3	22.8±0.2