Table 2. Pathogen-specific immunglobulin serostatus and serokinetics in paired samples from 64 CLL patients.
| CMV | VZV | EBV | |
|---|---|---|---|
| No. seropositive (%) | 45/64 (70.3) | 50/58 (86.2) | 56/58 (96.6) |
| No. seroconversion from positive to negative (%) | 0/45 (0) | 9/50 (18.0) | 2/56 (3.6) |
| No. seroconversion from negative to positive | 0 | 1 | 0 |
| Decay of virus-specific Ab per year; mean (SD)1 | 0.017 (0.06) | 0.029 (0.12) | 0.033 (0.05) |
1
Decay of total IgG per year; mean (SD): 0.03 (0.03).
Seropositivity was determined in the first sample collected from the respective patient, conversion of serostatus was determined by comparing qualitative test results for paired samples per patient. Mean interval between the collection of the two samples was 4.63 years (SD 1.99 years).