Table 1. Top five differentially expressed genes compared to xenograft.
| Top 5 upregulated genes compared to xenografts | Fold change | Top 5 downregulated genes compared to xenografts | Fold change | Number of differentially expressed genes, up + down, ≥ 2 fold | |
|---|---|---|---|---|---|
| MG4d | ALDH1A3 | 24.7 | VIM | 54.5 | 797 |
| C20orf100 | 15.2 | H19 | 33.8 | ||
| CALB2 | 12.7 | COL5A1 | 33.7 | ||
| IL8 | 11.9 | MX1 | 30.1 | ||
| RARRES1 | 7.8 | PMEPA1 | 24.5 | ||
| MG7d | ALDH1A3 | 29.0 | VIM | 34.6 | 473 |
| RARRES1 | 28.6 | COL5A1 | 32.4 | ||
| C20orf100 | 22.8 | H19 | 29.0 | ||
| CALB2 | 16.2 | TAGLN | 20.1 | ||
| TOX2 | 11.0 | PMEPA1 | 19.5 | ||
| PH4d | RARRES1 | 62.9 | VIM | 63.3 | 760 |
| S100P | 33.4 | TGFBI | 26.9 | ||
| ID1 | 25.3 | COL5A1 | 25.9 | ||
| ALDH1A3 | 15.5 | TAGLN | 16.2 | ||
| LXN | 12.6 | H19 | 15.4 | ||
| PH7d | RARRES1 | 75.6 | VIM | 63.1 | 952 |
| LCN2 | 38.5 | TGFBI | 33.7 | ||
| S100P | 32.6 | COL5A1 | 24.7 | ||
| ID1 | 26.2 | H19 | 20.2 | ||
| LXN | 13.9 | TAGLN | 19.2 | ||
| 2D | CALB2 | 23.6 | VIM | 64.9 | 2428 |
| ID1 | 17.1 | H19 | 27.9 | ||
| ALDH1A3 | 15.9 | COL5A1 | 26.6 | ||
| LOC100134265 | 15.5 | APOE | 13.6 | ||
| RARRES1 | 13.1 | IFIT1 | 13.5 |
Top five up- and downregulated genes and their fold changes in relation to xenograft expression values are shown. Number of up- and downregulated genes is largest in the 2D model.