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HER2/neu Expression in Esophageal/Gastroesophageal Junction Adenocarcinoma Biopsy Specimens
| Manual Quantitative HER2/neu IHC Score | No.
|
Total, No. (%) | ||
|---|---|---|---|---|
| Grade 1 | Grade 2 | Grade 3 | ||
| 0 | 1 | 4 | 4 | 9 (30) |
| 1+ | 2 | 3 | 1 | 6 (20) |
| 2+ | 1 | 1 | 0 | 2 (7) |
| 3+ | 3 | 4 | 6 | 13 (43) |
| Total | 7 | 12 | 11 | 30 (100) |
| HER2/neu overexpression (IHC 3+), % | 43 | 33 | 55 | |
| Overall cases with HER2/neuoverexpression: 13/30 (43%) | ||||
Abbreviations: HER2/neu, human epidermal growth factor receptor 2; IHC, immunohistochemistry.
