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. Author manuscript; available in PMC: 2013 Oct 23.
Published in final edited form as: Arch Pathol Lab Med. 2012 Jun;136(6):610–617. doi: 10.5858/arpa.2011-0371-OA

Table 6.

Concordance Between the Results of Manual HER2/neu Immunohistochemistry (IHC) Score and Automated HER2/neu IHC Image Analysis Interpretation in Gastric Adenocarcinoma Biopsy Specimens

Manual HER2/neu IHC Score HER2/neu IHC Image Analysis Interpretation
Concordance Rate, %
Negative/Favorable (≤1.7) Equivocal/Intermediate (>1.7 to <3.0) Positive/Unfavorable (≥3.0)
0 16 0 0 100
1+ 2 0 0 100
2+ 2 0 0 0
3+ 5 1 1 14
Average digital score 0.6 2.3 4.0

Abbreviation: HER2/neu, human epidermal growth factor receptor 2.