. Author manuscript; available in PMC: 2013 Oct 23.

Published in final edited form as: Arch Pathol Lab Med. 2012 Jun;136(6):610–617. doi: 10.5858/arpa.2011-0371-OA

Table 8.

Concordance Between the Results of Manual HER2/neu Immunohistochemistry (IHC) Score and Automated HER2/neu IHC Image Analysis Interpretation in Esophageal/Gastroesophageal Junction Adenocarcinoma Biopsy Specimens

Manual HER2/neu IHC Score	HER2/neu IHC Image Analysis Interpretation			Concordance Rate, %
Manual HER2/neu IHC Score	Negative/Favorable (≤1.7)	Equivocal/Intermediate (>1.7 to <3.0)	Positive/Unfavorable (≥3.0)	Concordance Rate, %
0	9	0	0	100
1+	6	0	0	100
2+	2	0	0	0
3+	6	2	5	38
Average digital score	0.7	2.5	4.0

Abbreviation: HER2/neu, human epidermal growth factor receptor 2.