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. 2013 Oct 23;33(43):16874–16888. doi: 10.1523/JNEUROSCI.4654-12.2013

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Copyright © 2013 the authors 0270-6474/13/3316874-15$15.00/0

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Figure 9. — Acoustic startle and PPI. A, Mice were tested for startle response and habituation over five startle events using 110 dB white noise. Animals from LPS-challenged pregnancies showed reduced startle amplitude (p = 0.002 for treatment effect by two-way ANOVA, n = 19 males, 16 females from 5 pregnancies for saline; 17 males, 22 females from 8 pregnancies for LPS). Mice displayed normal habituation to the startle tone. B, PPI was measured over a range of 68–80 dB prepulses. Offspring from LPS-challenged pregnancies showed no significant change in the percentage PPI (p = 0.29 for treatment effect by two-way ANOVA).