Fig. 4.

The effects of SNC80 on the neurokinin 1 receptor (NK1R) internalization induced by exogenous substance P. (A) Percentage of NK1R (+) neurons showing internalization in lamina I of the lumbar spinal cord 30 minutes after intrathecal SP. Rats were treated with intrathecal substance P or saline. (B) Percentage of NK1R (+) neurons showing internalization in lamina I of the lumbar spinal cord. Rats were treated with intrathecal vehicle or SNC80 before receiving intrathecal substance P. Data are presented as mean ± S.E.M. n = 3, *P < 0.05