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The effect of FICZ treatment on CYP1A1 and UGT expression in HaCaT cells. Total RNA was isolated from HaCaT cells that were treated with FICZ for 6 hours. Complementary DNA was synthesized, and then qRT-PCR was carried out for human CYP1A1 (A) and UGT (B). Concentration-dependent effects of FICZ on UGT1A1 expression was also analyzed (C). Each column is the mean ± S.D. of three independent determinations. C, control. *P < 0.05, compared with the expression in the control HaCaT cells.
