Table 1.

Serum lipid profiles of WT and N1^+/− mice treated with vehicle or pitavastatin (mmol/l)

Treatment	T-CHO	HDL-C	TG
WT(Vehicle)	1.71 ± 0.07	0.83 ± 0.02	1.11 ± 0.15
N1+/− (Vehicle)	2.25 ± 0.07*	1.37 ± 0.10	1.05 ± 0.06
WT (Pitavastatin 3 mg/kg per day)	1.29 ± 0.14	0.54 ± 0.03	0.56 ± 0.01
N1+/− (Pitavastatin 3 mg/kg per day)	1.34 ± 0.12	0.67 ± 0.03	0.51 ± 0.09

Abbreviations: HDL-C, high-density lipoprotein cholesterol; T-CHO, total cholesterol; TG, triglycerides.

Data are shown as mean ± s.d.

^*P<0.001, compared with WT with vehicle. n = 5 for each group.