Table 2.

Blood serum marker levels for prediction of disease type: results of bivariate and multivariate multinomial logistic regression analyses^a

Cytokine or chemokine	Analysis of suspected vs evident Lyme neuroborreliosis				Analysis of TBE vs evident Lyme neuroborreliosisb
	Bivariate		Multivariate		Bivariate		Multivariate
	OR (95% CI)c	P	OR (95% CI)	P	OR (95% CI)	P	OR (95% CI)	P
CXCL13	0.98 (0.97–0.99)	< 0.001	0.98 (0.97–0.99)	< 0.001	0.99 (0.99–1)	0.18	0.99 (0.98–0.99)	0.05
IL-8	1 (1–1)	0.35			1 (1–1)	0.63
IL-1β	1.05 (0.95–1.16)	0.35			1.06 (0.95–1.17)	0.29
IL-6	1 (1–1.01)	0.35			0.99 (0.97–1.01)	0.34
IL-10	1.29 (0.91–1.82)	0.16	1.62 (1.06–2.46)	0.03	1.72 (1.18–2.5)	0.004	1.96 (1.26–3.04)	<0.001
IL-12p70	1.09 (0.89–1.33)	0.41			1.12 (0.92–1.37)	0.26
IFN-γ	0.93 (0.81–1.07)	0.31			0.9 (0.76–1.06)	0.22
TNF-α	1 (0.93–1.08)	0.98	1.05 (0.9–1.21)	0.54	0.86 (0.75–1)	0.04	1.01 (0.83–1.23)	0.93
IL-5	0.94 (0.86–1.02)	0.15			0.96 (0.88–1.04)	0.32
IL-4	1 (0.98–1.01)	0.77	1 (0.98–1.01)	0.67	0.85 (0.73–1)	0.05	0.87 (0.71–1.07)	0.20
IL-2	0.99 (0.93–1.06)	0.86			1.01 (0.94–1.08)	0.89

^aStatistically significant odds ratios (ORs) are in bold type.

^bTBE, tick-borne encephalitis.

^cCI, confidence interval.