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A, Survival of islet allografts from MHC class II KO C57BL/6 mice in thymectomized and CD8+ T cell-depleted BALB/c recipients that were treated with anti-IL-12 mAb. B, Intragraft Th1 (IFN-γ)/ Th2 (IL-4) gene transcript analysis in control Ab- or anti-IL-12-treated recipients.
