Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
UL36USP inhibits the IFN-β promoter activity between the level of MAVS and TBK1/IKKε. HEK293T cells were cotransfected with IFN-β-Luc reporter, PRL-TK and RIG-IN (A), IPS-1 (B), TBK1 (C), IKKε (D), or IRF3/5D (E) expression plasmids along with UL36USP expression plasmid. Luciferase activity was analyzed as described for Fig. 1A. The data represent means ± standard deviations for three replicates. Statistical analysis was performed using the t test. *, P < 0.05.
