Overview of the conservation of Ac83 domains. The predicted domains of Ac83 are indicated in the scheme. Alignments of the CBD, TM, PR, and putative C2HC zinc finger regions of Ac83 homologs are shown. The Ac83 homologs of GVs are marked with asterisks. The cysteine and histidine residues that define the C2HC zinc finger are shown below the alignment. Black shading denotes 100% conservation. Dark gray and light gray shading represent 80 and 60% conservation, respectively. The alignment was performed using ClustalX and was edited with GeneDoc software. PlxyNPV, Plutella xylostella NPV; BmNPV, Bombyx mori NPV; OpNPV, Orgyia pseudotsugata NPV; SfNPV, Spodoptera frugiperda NPV; SpltNPV, Spodoptera litura NPV; TnSNPV, Trichoplusia ni single NPV; HearNPV, Helicoverpa armigera NPV; NeabNPV, Neodiprion abietis NPV; NeleNPV, Neodiprion lecontei NPV; NeseNPV, Neodiprion sertifer NPV; CuniNPV, Culex nigripalpus NPV; CpGV, Cydia pomonella GV; CrleGV, Cryptophlebia leucotreta GV.