Fig 1.

KF11 Gag is targeted significantly more by individuals expressing HLA-B*57:01 or HLA-B*57:03 than by those expressing HLA-B*58:01. Data were extracted from a large C-clade cohort of 1,010 chronically HIV-infected individuals from Durban, South Africa, and a B-clade cohort from Oxford, United Kingdom. HLA-B*57:01-, HLA-B*57:03-, and HLA-B*58:01-expressing individuals were mutually excluded from groups expressing the other two HLA-B alleles. The 18-mer overlapping peptide containing KF11 (underlined), WVKVIEEKAFSPEVIPMF, was used to identify ex vivo IFN-γ ELISpot responses. P values were determined by Fisher's exact test.