Table 1. Hormone levels.
Mean±SEM (pg/ml) | P-values AN vs. ANWR |
||||||
---|---|---|---|---|---|---|---|
AN | ANWR | HC | AN vs. HC | ANWR vs. HC |
Overall | ||
Serum Cortisol | |||||||
T 0 Fasting | 15.9±1.4 | 12.9±1.0 | 11.7±1.1 | NS | 0.013 | NS | 0.041 |
T 30 | 15.1±1.6 | 11.3±1.08* | 11.7±0.8 | - | - | - | 0.089 |
T 60 | 13.3±1.5* | 11.5±0.7 | 10.9±0.8 | - | - | - | NS |
T120 | 12.9±1.3* | 11.1±0.8 | 8.8±0.7* | NS | 0.006 | 0.067 | 0.019 |
Nadira | 11.7±1.1* | 9.9±0.7* | 8.4±0.6* | NS | 0.008 | NS | 0.028 |
AUC | 1679±159 | 1383±83 | 1280±73 | - | - | - | 0.084 |
Plasma ACTH | |||||||
T 0 Fasting | 27.4±2.3 | 26.0±2.1 | 21.3±1.3 | - | - | - | NS |
T 30 | 23.6±3.0 | 25.6±1.9 | 22.4±1.4 | - | - | - | NS |
T 60 | 21.8±1.7 | 29.8±3.1 | 21.9±1.2 | 0.017 | NS | 0.024 | 0.033 |
T 120 | 23.2±1.7 | 26.2±1.7 | 19.6±1.2 | 0.098 | - | 0.006 | 0.023 |
Nadira | 20.9±1.9 | 24.2±1.6 | 19.0±1.2* | - | - | - | 0.074 |
AUC | 2689±262 | 3286±247 | 2563±135 | - | - | - | 0.096 |
p<0.05 compared to T0
nadir, minimum post-meal level