Table I.
Activations for painful grasps, main effects of actions, object, and the interaction, thresholded at P < 0.005
| Contrast/region | Peak coordinates (Talairach, x,y,z) | Maximum t‐score | Cluster size (mm3) |
|---|---|---|---|
| Painful grasp (pain grasp > all) | |||
| SFG | −18, 50, 22 | 4.82 | 349 |
| MFG | −39, 38, 13 | 5.84 | 954 |
| IFG | −51, 11, 13 | 4.20 | 136 |
| PCG/IPL | −48, −25, 34 | 7.13 | 4,174 |
| PCG/IPL | 54, −22, 37 | 4.40 | 336 |
| Superior postcentral (SI) | −30, −37, 40 | 7.63 | 1,954 |
| Superior postcentral (SI) | 33, −31, 37 | 4.59 | 202 |
| Posterior parietal | −12, −52, 55 | 5.00 | 232 |
| Posterior parietal | 27, −43, 49 | 4.85 | 365 |
| Ventral occipital cortex | 36, −58, −8 | 6.85 | 5,189 |
| Ventral occipital cortex | 36, −79, 1 | 6.84 | 6,522 |
| Ventral occipital cortex | −12, −82, −8 | 4.58 | 1,031 |
| Main effect of action (grasp > withdraw) | |||
| PCG/IPL | 63, −19, 36 | 5.41 | 96 |
| PCG/IPL | −63, −28, 28 | 5.05 | 1,158 |
| PCC | −6, −31, 37 | 4.97 | 258 |
| PMTC/LOC | 45, −55, −5 | 8.80 | 1,439 |
| Ventral occipital cortex | 36, −82, 4 | 6.71 | 5,125 |
| Ventral occipital cortex | −9, −85, −14 | 5.46 | 581 |
| Main effect of action (withdraw > grasp) | |||
| Putamen | 21, 5, 13 | 4.99 | 380 |
| Ventral occipital cortex | −9, −70, −8 | 5.98 | 631 |
| Main effect of object (noxious > neutral) | |||
| Temporal pole | 39, 11, −11 | 5.13 | 169 |
| PCG/IPL | −51, −25, 31 | 5.37 | 265 |
| IPL | −63, −25, 37 | 4.64 | 322 |
| Paracentral lobule | −15, −25, −52 | 5.21 | 206 |
| Cerebellum | −18, −52, −14 | 7.98 | 683 |
| Cerebellum | −1, −58, −29 | 5.78 | 191 |
| Cerebellum | −9, −64, −14 | 4.68 | 563 |
| Ventral occipital cortex | 18, −73, −11 | 6.06 | 2,214 |
| Occipital cortex | −18, −79, 13 | 5.26 | 508 |
| PMTC/LOC | 30, −88, 4 | 10.36 | 3,848 |
| PMTC/LOC | −30, −82, −2 | 4.59 | 276 |
| Interaction of object and action (appropriate > inappropriate actions) | |||
| Superior frontal | −15, 53, 25 | 6.26 | 401 |
| Frontal | 27, 44, 28 | 4.70 | 163 |
| IFG | −51, 17, 4 | 5.20 | 547 |
| IFG | −27, 29, 4 | 4.93 | 156 |
| IFG | 52, 17, 1 | 4.56 | 174 |
| Midcingulate | 0, −10, 52 | 5.66 | 311 |
| Superior parietal | −9, −55, 58 | 5.25 | 1,087 |
| Superior parietal | 21, −49, 58 | 4.21 | 300 |
| PMTC/LOC | −42, −61, 7 | 4.86 | 392 |
| Cerebellum | 24, −73, −32 | 5.45 | 385 |
| Cerebellum | 27, −61, −23 | 4.85 | 305 |
Contrasts were whole‐brain corrected at a family‐wise alpha of 0.05. For each contrast, activations are ordered from rostral to caudal.
IPL, inferior parietal lobule; PCC, posterior cingulate cortex; PCG, postcentral gyrus; LOC, lateral occipital complex; MFG, middle frontal gyrus; PMTC, posterior middle temporal cortex; SFG, superior frontal gyrus; IFG, inferior frontal gyrus.