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. Author manuscript; available in PMC: 2014 Oct 1.
Published in final edited form as: Biochem Pharmacol. 2013 Aug 18;86(7):10.1016/j.bcp.2013.08.013. doi: 10.1016/j.bcp.2013.08.013

Fig. 4.

Fig. 4

Fragmentation analysis of MS/MS spectra for M1–M6. Human liver microsomes (1 mg/mL) were incubated with 10 μM dapivirine for 30 min at 37 °C in the presence of a NADPH-regenerating system. Metabolites were detected and fragmented using uHPLC-MS/MS in product ion mode. From left to right, then top to bottom are M1, M2, M3, M4, M5, and M6.