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. Author manuscript; available in PMC: 2014 Oct 1.
Published in final edited form as: Biochem Pharmacol. 2013 Aug 18;86(7):10.1016/j.bcp.2013.08.013. doi: 10.1016/j.bcp.2013.08.013

Fig. 5.

Fig. 5

Relative contributions to total metabolite profile when dapivirine or dapivirine-d11 are incubated with human liver microsomes (1 mg/mL) for 60 min at 37 °C in the presence of an NADPH-regenerating system and UDPGA. All metabolites were detected in product ion mode. The experiment was carried out in triplicate. ** = p ≤ 0.01.