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CRK-SH3N domain expression enhances PAK1 phosphorylation in the PAK1 kinase inhibitory domain. Western blot demonstrating PAK1 and phospho-PAK1 Ser144 in A549 cells expressing the CRK-SH3N domain or empty vector. Quantification of the phospho-PAK1 Ser144 signal in cells relative to the signal of cell expressing empty vector is shown.
