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. Author manuscript; available in PMC: 2014 Jul 9.
Published in final edited form as: Circulation. 2013 Jun 11;128(2):10.1161/CIRCULATIONAHA.112.001075. doi: 10.1161/CIRCULATIONAHA.112.001075

Figure 1.

Figure 1

Experimental protocol. Three groups of pigs were studied (groups I–III). Four days after a baseline echocardiogram, pigs underwent a 90-min coronary occlusion followed by reperfusion or sham surgery. At three to four months after MI (97 ± 12 d in vehicle-treated and 96 ± 6 d in CSC-treated groups), pigs received intracoronary infusion of vehicle (group II), or autologous CSCs into the infarct-related artery using a balloon catheter (group III). Group I served as noninfarcted controls. Echocardiographic and hemodynamic assessment of cardiac function was performed before treatment and at the time of sacrifice. At 31 days after vehicle/CSC therapy, pigs were euthanized for morphometric and histological studies.