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. 2013 Oct 1;382(1):15–26. doi: 10.1016/j.ydbio.2013.08.004

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© 2013 The Authors

Open Access under CC BY 3.0 license

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Fig. 3 — Sox2 is dispensable for dermal papilla formation and hair follicle morphogenesis. (A–B, K, L) Wholemounts of E16.5 and P2 skin from Blimp1Cre−/Sox2flHom (A, K) and Blimp1Cre+/Sox2flHom (B, L) mice labelled with the antibodies indicated. Guard/awl/auchene hair follicles are marked with arrows. (C–J, M–T) Cryosections of E16.5 and P2 skin from Blimp1Cre−/Sox2flHom (C, E, G, I, M, O, S) and Blimp1Cre+/Sox2flHom (D, F, H, J, N, P, R, T) mice immunostained with the antibodies indicated. Arrows mark guard/awl/auchene hair follicles. Scale bars: 100 μm. (U, V) Quantitation of hair follicle density (U) and number of cells per DP (V) in Blimp1Cre-/Sox2flHom (Wt) and Blimp1Cre+/Sox2flHom (Sox2KO) E18.5 embryonic skin. N=3 embryos per genotype. The number of cells per DP of 11 hair follicles of each type was counted per embryo.