Fig. 4.

Sox2 is required for postnatal awl/auchene hair follicles. (A–B) E18.5 embryonic skin from Blimp1Cre-/Sox2flHom (A) and Blimp1Cre+/Sox2flHom (B) mice grafted on the back of NSG mice. (C–F) Grafts were harvested at 10 weeks. Guard (C), awl (D), auchene (E) and zigzag (F) hair follicle length was the same in Sox2+ and Sox2− grafts. (G) Medulla cell width was not affected by Sox2 deletion. (H) Quantitation of hair follicle types distinguished on the basis of medulla cell width and hair follicle length (biological replicates n=4). ***P<0.003.