Table 1.
Structural similarity of the IFN-γ receptor molecules (IFN-γ-Rx) at and outside the interface with IFN-γ. Four receptor chains from crystal structures 1fg9 [17] and 1fyh [29] are compared to receptor chain D of 1fg9.
| PDB | rmsd (Å)a | rmsd (Å)b |
|---|---|---|
| Code:chain | 40 interface residues | 40 random residues |
| 1fg9:C | 0.60 | 1.66 |
| 1fg9:E | 4.16 | 4.32 |
| 1fyh:B | 0.58 | 1.42 |
| 1fyh:E | 0.59 | 1.06 |
aRoot mean square deviations (rmsd) between the four IFN-γ-Rx molecules (labeled PDB_ID:chain) and the chain D of 1fg9. Deviations are calculated between the positions of the main chain atoms of the 40 residues forming the interface with IFN-γ.
bRoot mean square deviations (rmsd) between the four IFN-γ-Rx molecules (labeled PDB_ID:chain) and the chain D of 1fg9. Deviations are calculated between the positions of the main chain atoms randomly selected outside the 40 residues forming the interface with IFN-γ.