Table 1.
Demographic and cognitive characteristics in the whole sample, disaggregated for increased levels of alpha3/alpha2 Numbers denote mean ± standard deviation, number and [range].
| Alpha3/alpha2 |
||||
|---|---|---|---|---|
| High | Middle | Low | p | |
| Demographic and clinical futures | ||||
| Number of subjects | 18 | 38 | 18 | – |
| Age, years | 70.4 ± 6.7 [60–85] | 68.4 ± 8.2 [52–83] | 70.4 ± 7.4 [57–80] | .55 |
| Sex, female | 13 (%) | 24 (%) | 14 (%) | .51 |
| Education, years | 6.6 ± 3.6 [4–18] | 7.6 ± 3.7 [3–17] | 8.3 ± 4.7 [3–18] | .42 |
| Mini Mental State Exam | 27 ± 1.7 [23–29] | 27.4 ± 1.3 [24–30] | 26.9 ± 1.2 [23–30] | .46 |
| WMHs (mm3) | 2.78 ± 2.58 | 5.59 ± 6.60 | 2.57 ± 2.76 | .09 |
| Alpha3/alpha2 | 1.29 ± 0.1 [1.17–1.52] | 1.08 ± 0.0 [1–1.16] | 0.9 ± 0.1 [0.77–0.98] | .000 |
| Memory | ||||
| Babcock | 9.6 ± 3.5 | 9.8 ± 4.1 | 9.9 ± 3.8 | .99 |
| AVLT. immediate recall | 42.7 ± 7.6 | 38.8 ± 11.8 | 40.5 ± 12.8 | .53 |
| AVLT. delayed recall | 8.6 ± 3.2 | 8.2 ± 4.1 | 9.1 ± 4.4 | .80 |
| Rey’s figure. recall | 15 ± 6.9 | 12.6 ± 6.1 | 15 ± 7 | .35 |
| Language | ||||
| Fluency phonetic | 31.9 ± 7.4 | 33.1 ± 9.8 | 34.1 ± 9.5 | .80 |
| Fluency semantic | 36.1 ± 6.4 | 33.7 ± 8.3 | 34.1 ± 9.8 | .62 |
| Token test | 31.1 ± 2.4 | 32.2 ± 2.4 | 33.1 ± 2 | .06 |
| Constructional and visuo-spatial abilities | ||||
| Rey’s figure copy | 31.7 ± 5.3 | 31.4 ± 7.8 | 29.1 ± 9.9 | .58 |
| Attention and executive functions | ||||
| Trail Making Test A | 39.4 ± 21.5 | 37.1 ± 23.6 | 65 ± 51 | .20 |
| Trail Making Test B | 117.1 ± 77.5 | 93 ± 77.1 | 120.7 ± 99.4 | .48 |
| Non verbal reasoning | ||||
| Raven test | 24.8 ± 3.8 | 26.3 ± 5.8 | 26.9 ± 4.5 | .44 |
p denotes significance on ANOVA.