Table 6. Summary of the Hit Rates for the 240 Compounds Screened against BRD4.
approach | compounds tested | hits | hit rate (%) |
---|---|---|---|
all compounds | 240 | 6 | 2.5 |
virtual screen | 143 | 6 | 4.2 |
literature substructures | 76 | 2 | 2.6 |
similarity searching | 67 | 4 | 6.0 |
control set | 97 | 0 | 0 |