. Author manuscript; available in PMC: 2014 Nov 1.

Published in final edited form as: Magn Reson Imaging. 2013 Aug 15;31(9):10.1016/j.mri.2013.07.002. doi: 10.1016/j.mri.2013.07.002

Table 4.

Analysis of imaging parameter changes (from pretreatment to after cycle 1) for discriminating pCR.

Imaging parameter	% change for patients with a pCR		% change for patients without a pCR		p-value for discriminating patients with a pCR
	Median	Range	Median	Range	p-value for discriminating patients with a pCR
Lesion size (mm)
LAD (early)	−17	−53 to +6	−4	−34 to +18	.08
SAD (early)	−11	−61 to +33	−12	−23 to +24	.70
LAD (late)	−15	−39 to +10	0	−30 to +18	.11
SAD (late)	−12	−52 to +22	−8	−23 to +26	.25
Enhancement	0	−38 to 0	0	−17 to +17	.49
Kinetics
50% threshold
% progressive (Type I)	+ 49	+ 11 to +99	+ 28	−39 to+335	.75
% plateau (Type II)	−2	−39 to +36	−13	−51 to +47	.81
% washout (Type III)	−54	−84 to −12	−8	−86 to +50	.11
100% threshold
% progressive (Type I)	+ 62	+26to + 134	+16	−40 to +336	.35
% plateau (Type II)	−12	−56 to +26	−19	−86 to +61	.92
% washout (Type III)	−62	−90 to −26	−7	−97 to + 58	.04

Bold = statistically significant at p < .05. pCR = pathological complete response, LAD = long-axis diameter, SAD = short-axis diameter, − = percentage decrease, + = percentage increase.