TABLE 5.
Diagnostic properties of panel miRNAs and CD-related laboratory values
| miRNA | Sensitivity, % | Specificity, % | Correctly classified, % |
|---|---|---|---|
| miR-16 | 73.91 | 100 | 84.62 |
| miR-484 | 82.61 | 84.38 | 83.33 |
| miR-30e | 73.91 | 96.88 | 83.33 |
| miR-106a | 76.09 | 90.62 | 82.05 |
| miR-195 | 69.57 | 96.88 | 80.77 |
| miR-20a | 73.91 | 87.50 | 79.49 |
| miR-21 | 76.09 | 84.38 | 79.49 |
| miR-140 | 73.91 | 87.50 | 79.49 |
| let-7b | 82.61 | 75.00 | 79.49 |
| miR-192 | 78.26 | 78.12 | 78.21 |
| miR-93 | 71.74 | 84.38 | 76.92 |
| Test | Threshold | Sensitivity, % | Specificity, % | Correctly classified, % |
|---|---|---|---|---|
| CRP | 0.9 mg/dL | 63.64 | 93.55 | 76.00 |
| ASCA IgG | 10 U/mL | 62.22 | 80.65 | 69.74 |
| ESR | 20 mm/h | 52.17 | — | — |
| Alhnmin | 3.5 g/dL | 41.30 | — | — |
ASCA = anti-Saccharomyces cerevisiae antibody; CD = Crohn disease; CRP = C-reactive protein; ESR = erythrocyte sedimentation rate; miRNAs = microRNAs.