Table 2.
Mouse strain | Frequency of reactivation | Frequency of genome-positive cells | Reactivation efficiency (%)b | Frequency of persistent infection |
---|---|---|---|---|
PML−/− | 1/29,849 (1/25,319, 1/34,380)a | 1/848 (1/619, 1/1,078)a | 2.84% | 1/351,445 (1/238,334, 1/464,556)a |
PML+/+ | 1/84,050 (1/68,665, 1/99,435)a | 1/1,316 (1/958, 1/1,673)a | 1.57% | 1/2,827,263 (1/352,524, 1/5,302,002)a |
Fold increase | 2.8 (P < 0.001) | 1.55 (P = 0.03) | 1.8 | 8 (P < 0.001) |
Values in parentheses are upper and lower limits (95% confidence intervals).
Reactivation efficiency (%) = (frequency of reactivation/frequency of genome-positive cells) × 100.