Table 1.
Sample # | Stability* | Targeting** | % Gd-Tx Encap. (calculated) | % Gd-Tx Encap. (actual) | Charge (mV) | DLS Size (nm) |
---|---|---|---|---|---|---|
1 | UXL | UT | 0.54 | 0.51 | −17.70 | 88.90 |
2 | UXL | T | 0.53 | 0.50 | −17.74 | 88.80 |
3 | XL | UT | 0.52 | 0.52 | −10.73 | 87.50 |
4 | XL | T | 0.51 | 0.51 | −9.49 | 82.50 |
Micelles are stabilized with Fe(III) crosslinking (XL) reaction. UXL denotes uncrosslinked micelles.
Micelles are targeted (T) with an MC1R-specific ligand. UT denotes untargeted micelles.