Table 3.
Regression Weights of Indices of Vascular Risk 1
| Primary Sample (n=576) | ||||
|---|---|---|---|---|
| Variable | Beta | Standard Error | T | p-value |
| Age | −.17 | .038 | −4.57 | <.001 |
| Brain Volume | .08 | .052 | 1.62 | Not Significant |
| Race | .04 | .039 | .99 | Not Significant |
| Sex | .49 | .050 | 9.63 | <.001 |
| Current Smoking | −.01 | .038 | −.43 | Not Significant |
|
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| STEP 2 | ||||
|
| ||||
| Cardiometabolic Risk | −.11 | .042 | −2.63 | .009 |
| MetS | −.05 | .038 | −1.36 | Not Significant |
| Framingham Risk2 | −.15 | .060 | −2.51 | .01 |
| Carotid IMT | −.12 | .047 | −2.44 | .01 |
| Validation Sample (n=76) | ||||
|
| ||||
| Age | −.07 | .116 | −.59 | Not Significant |
|
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| Brain Volume | −.27 | .183 | −1.48 | Not Significant |
|
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| Race | −.09 | .121 | −.72 | Not Significant |
|
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| Current Smoking | .07 | .119 | .63 | Not Significant |
|
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| Sex | .14 | .179 | .79 | Not Significant |
| STEP 2 | ||||
|
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| Cardiometabolic Risk | −.36 | .113 | −3.20 | .002 |
|
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| MetS | −.32 | .112 | −2.84 | .006 |
|
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| Framingham Risk2 | −.13 | .216 | −.62 | Not Significant |
|
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| White Matter Hyperintensities | −.06 | .127 | −.48 | Not Significant |
1
Model initially shows demographic and CBF result, then in Step 2 showing effect of adding either CMR or other risk factor, e.g., Framingham Risk score. Beta is standardized weight.
2
Model included total Framingham Risk score, race, and total brain volume.