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. Author manuscript; available in PMC: 2014 Sep 15.
Published in final edited form as: Toxicology. 2013 Jul 8;311(3):10.1016/j.tox.2013.06.013. doi: 10.1016/j.tox.2013.06.013

Figure 2. Effect of p53 on NM-induced apoptotic epidermal cell death.

Figure 2

Skin sections from the study detailed in Figure 1 legend, were processed for TUNEL staining to determine apoptotic cell death as shown in representative pictures (A). Percent TUNEL positive cells were quantified by counting positive stained cells and the total number of cells in fifteen randomly selected fields per slide at 400× magnification as described under materials and methods. Data are presented as mean ± SEM of four animals in NM-exposed groups and three in respective controls. *, p < 0.05 as compared to controls. e, epidermis; d, dermis; Red arrows indicate TUNEL positive cells. Black scale bar = 100 µm.