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. Author manuscript; available in PMC: 2013 Oct 25.
Published in final edited form as: Sci Signal. 2011 Jun 28;4(179):10.1126/scisignal.2001497. doi: 10.1126/scisignal.2001497

Table 1.

Net change in overall phosphorylation in response to kinase inhibitors.

2.5-Fold
down-regulation (%)		 2.5-Fold
up-regulation (%)
Taxol 0.55 0.66
MLN8054, 0.25 µM 1.03 0.90
MLN8054, 1 µM 2.02 0.88
MLN8054, 5 µM 4.13 1.14
AZDZM 2.36 0.92
BI2536 mitosis 5.48 1.34
BI2536 entry 7.81 2.76