Table 4.
Approximate binding affinity of equine and canine influenza viruses.
Virus | 2,3SLN polymer | 2,6SLN polymer | ||
---|---|---|---|---|
App K D a | R 2 b | App K D | R 2 b | |
Eq/KY | 11 | .96 | NDBc | — |
Eq/CO | 5 | .99 | NDBc | — |
Ca/CO-1 | 5 | .99 | NDBc | — |
Ca/CO-2 | 2 | .94 | NDBc | — |
Ca/WY | 2 | .95 | NDBc | — |
A/Syd | 139 | .97 | 10 | .99 |
aApproximate dissociation constant (K D) values are from one representative experiment. Lower K D values represent a higher binding affinity for that polymer (K D is expressed in nM−1 sialic acid). Repeated experiments yielded similar results.
b R 2: coefficient of determination.
cNDB: no detectable binding.