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. Author manuscript; available in PMC: 2013 Oct 25.
Published in final edited form as: J Cancer Ther. 2013 May;4(3):10.4236/jct.2013.43094. doi: 10.4236/jct.2013.43094

Table 2.

Correlation among cancers that express high MALAT1 transcripts, involve p53 deregulation and are associated with DNA tumor virus infection.

Human carcinomas p53 status MALAT-1 over-expressed
Endometrial Stromal Sarcoma[7] P53 nuclear accumulation[44] Yes
Hepatocellular Carcinoma[5] P53 mutation[5] Yes
Non Small Cell Lung Cancer[1] P53 mutation[12] Yes
HIV-Salivary Gland Disease (premalignant) N/D Yes
Osteosarcoma[4] P53 mutation[45] Yes
Breast[5] P53 nuclear accumulation[46] Yes
Pancreas[5] P53 mutation[47] Yes
Colon[5] P53 mutation[48] Yes
Late-Stage Prostate Cancer[5] P53 mutation[49] Yes
Cervical (CaSki cell line) [41] HPV inhibits P53 activity[50] Yes
Endometrial Stromal Sarcoma [7] P53 nuclear accumulation[44] Yes
Hepatocellular Carcinoma[5] P53 mutation[5; 45] Yes
Non Small Cell Lung Cancer[1] P53 mutation[12] Yes
HIV-Salivary Gland Disease (premalignant) N/D Yes
Osteosarcoma[4] P53 mutation[46] Yes
Breast[5] P53 nuclear accumulation [47] Yes
Pancreas [5] P53 mutation[48] Yes
Colon[5] P53 mutation[49] Yes
Late-Stage Prostate Cancer[5; 45] P53 mutation[50; 51] Yes
Cervical (CaSki cell line)[43] HPV inhibits P53 activity[52] Yes