Table 3.
Overall Survival from Adjuvant Treatment
| Factor | Median (months) |
1-year | 2-year | 3-year | p-value | |
|---|---|---|---|---|---|---|
| All patients, N=86 | 22 | 76% | 43% | 23% | ||
| Age | > 70years | 16 | 54% | 33% | 12% | 0.147 |
| ≤ 70years | 23 | 84% | 46% | 28% | ||
| Tumor grade | Well/moderately differentiated | 23 | 81% | 47% | 24% | 0.651 |
| Poorly differentiated | 20 | 63% | 37% | 21% | ||
| Tumor size | >3cm | 19 | 71% | 40% | 17% | 0.281 |
| ≤3cm | 23 | 77% | 43% | 25% | ||
| Tumor location | Head | 22 | 74% | 41% | 24% | 0.793 |
| Body/Tail | 18 | 81% | 48% | 21% | ||
| Lymph nodes | Positive | 19 | 72% | 36% | 16% | 0.016 |
| Negative | 29 | 83% | 55% | 37% | ||
| Resection margins |
Positive (including <1 mm) | 19 | 76% | 36% | 20% | 0.250 |
| Negative | 24 | 76% | 48% | 26% | ||
| Adjuvant Treatment |
Chemo-RT only | 17 | 61% | 33% | 13% | 0.080 |
| Chemo-RT + gemcitabine | 24 | 85% | 50% | 33% | ||
| Chemo-RT only | 17 | 61% | 33% | 13% | 0.552 | |
| Chemo-RT + non-gem chemo* | 18 | 91% | 45% | 18% | ||
| Chemo-RT only | 17 | 61% | 33% | 13% | 0.092 | |
| Chemo-RT + any chemo | 23 | 86% | 49% | 30% | ||
Abbreviations: Chemo-RT= Concurrent chemotherapy and radiation therapy
*
non-gemcitabine based chemotherapy