Table 4.
Disease-free Survival from Adjuvant Treatment
| Factor | Median (months) |
1-year | 2-year | 3-year | p-value | |
|---|---|---|---|---|---|---|
| All patients, N=86 | 10 | 44% | 23% | 12% | ||
| Age | > 70years | 9 | 38% | 13% | 13% | 0.366 |
| ≤ 70years | 11 | 47% | 27% | 12% | ||
| Tumor grade | Well/moderately differentiated | 11 | 43% | 24% | 9% | 0.886 |
| Poorly differentiated | 9 | 43% | 20% | 13% | ||
| Tumor size | >3cm | 9 | 31% | 14% | 6% | 0.102 |
| <3cm | 13 | 52% | 28% | 14% | ||
| Tumor location | Head | 11 | 49% | 24% | 14% | 0.128 |
| Body/Tail | 10 | 29% | 19% | 6% | ||
| Lymph nodes | Positive | 10 | 40% | 19% | 6% | 0.131 |
| Negative | 14 | 52% | 30% | 23% | ||
| Resection margins |
Positive (including <1 mm) | 9 | 37% | 16% | 7% | 0.083 |
| Negative | 13 | 51% | 28% | 16% | ||
| Adjuvant Chemo |
Chemo-RT only | 8 | 33% | 17% | 7% | 0.044 |
| Chemo-RT + gemcitabine | 12 | 51% | 30% | 13% | ||
| Chemo-RT only | 8 | 33% | 17% | 7% | 0.396 | |
| Chemo-RT + non-gem chemo* | 13 | 55% | 18% | 18% | ||
| Chemo-RT only | 8 | 33% | 17% | 7% | 0.047 | |
| Chemo-RT + any chemo | 13 | 52% | 27% | 15% | ||
Abbreviations: Chemo-RT= Concurrent chemotherapy and radiation therapy
*
non-gemcitabine based chemotherapy