Table 5.
Locoregional Recurrence following Adjuvant Treatment
| Factor | 1-year | 2-year | 3-year | p-value | ||
|---|---|---|---|---|---|---|
| All patients, N=86 | 17% | 33% | 36% | |||
| Age | > 70years | 23% | 46% | 46% | 0.347 | |
| ≤ 70years | 15% | 30% | 33% | |||
| Tumor grade | Well/moderately differentiated | 18% | 32% | 36% | 0.846 | |
| Poorly differentiated | 17% | 33% | 33% | |||
| Tumor size | >3cm | 23% | 43% | 49% | 0.126 | |
| ≥3cm | 14% | 25% | 25% | |||
| Tumor location | Head | 14% | 30% | 33% | 0.361 | |
| Body/Tail | 26% | 41% | 41% | |||
| Lymph nodes | Positive | 14% | 38% | 42% | 0.384 | |
| Negative | 22% | 26% | 26% | |||
| Resection margins |
Positive (including <1 mm) | 19% | 31% | 31% | 0.965 | |
| Negative | 15% | 34% | 39% | |||
| Adjuvant Chemo |
Chemo-RT only | 30% | 39% | 45% | 0.078 | |
| Chemo-RT + gemcitabine | 11% | 25% | 25% | |||
| Chemo-RT only | 30% | 39% | 45% | 0.470 | ||
| Chemo-RT + non-gem chemo* | 0% | 42% | 42% | |||
| Chemo-RT only | 30% | 39% | 45% | 0.080 | ||
| Chemo-RT + any chemo | 9% | 29% | 29% | |||
Abbreviations: Chemo-RT= Concurrent chemotherapy and radiation therapy
*
non-gemcitabine based chemotherapy