Table 6.
Distant Failure following Adjuvant Treatment
| Factor | 1-year | 2-year | 3-year | p-value | |
|---|---|---|---|---|---|
| All patients, N=86 | 50% | 74% | 87% | ||
| Age | > 70years | 58% | 83% | 83% | 0.315 |
| ≤ 70years | 47% | 71% | 87% | ||
| Tumor grade | Well/moderately differentiated | 49% | 72% | 89% | 0.629 |
| Poorly differentiated | 53% | 78% | 86% | ||
| Tumor size | >3cm | 63% | 81% | 92% | 0.164 |
| <3cm | 42% | 69% | 85% | ||
| Tumor location | Head | 48% | 75% | 86% | 0.751 |
| Body/Tail | 57% | 71% | 89% | ||
| Lymph nodes | Positive | 56% | 79% | 94% | 0.060 |
| Negative | 38% | 64% | 73% | ||
| Resection margins |
Positive (including <1 mm) | 56% | 81% | 92% | 0.120 |
| Negative | 44% | 68% | 81% | ||
| Adjuvant Chemo |
Chemo-RT only | 58% | 79% | 90% | 0.114 |
| Chemo-RT + gemcitabine | 44% | 69% | 87% | ||
| Chemo-RT only | 58% | 79% | 90% | 0.342 | |
| Chemo-RT + non-gem chemo* | 45% | 77% | 77% | ||
| Chemo-RT only | 58% | 79% | 90% | 0.100 | |
| Chemo-RT + any chemo | 44% | 71% | 84% | ||
Abbreviations: Chemo-RT= Concurrent chemotherapy and radiation therapy
*
non-gemcitabine based chemotherapy