Figure 2.

Gradient-loaded liposomes are stable with good payload retention in vitro. Liposomes suspended in (A) PBS and (B) human serum. Graphs show results of duplicate tests. Retention was measured after incubation in PBS/serum at room temperature for a range of times. Virtually 100% staurosporine was contained within the liposomes by 3 hours of incubation in PBS or serum, with approximately 80% of the staurosporine remaining after 6 hours of incubation. Red = expt 1; blue = expt 2.

Abbreviation: PBS, phosphate-buffered saline; expt, experiment.