Table 3.
Summary of the ACRs (%py) from MCI or a-MCI to AD stratified by selected study characteristics
| Characteristic | ACR |
|||||
|---|---|---|---|---|---|---|
| author reported |
author reported or deriveda |
|||||
| k | range | median | k | range | median | |
| Population | ||||||
| Overall | 14 | 5.4–16.5 | 8.9 | 24 | 4.3–18.8 | 8.4 |
| MCI | 7 | 5.4–11.5 | 9.2 | 12 | 4.3–11.5 | 8.4 |
| a-MCI | 7 | 5.6–16.5 | 8.5 | 12 | 5.6–18.8 | 8.4 |
| Clinic | ||||||
| Overall | 7 | 7.5–16.5 | 11.0 | 13 | 5.9–18.8 | 10.2 |
| MCI | 4 | 7.5–11 | 10.1 | 5 | 7.5–11 | 9.7 |
| a-MCI | 3 | 11–16.5 | 11.6 | 8 | 5.9–18.8 | 10.6 |
| Community | ||||||
| Overall | 7 | 5.4–11.5 | 7.1 | 11 | 4.3–11.5 | 6.0 |
| MCI | 3 | 5.4–11.5 | 6.0 | 7 | 4.3–11.5 | 5.5 |
| a-MCI | 4 | 7.4–8.9 | 8.5 | 4 | 5.6–8.5 | 7.3 |
k = Number of studies.
a
Incident AD cases/person-time. If necessary estimated person-time = mean follow-up time × number of patients at baseline.